Occupational, Environmental, and Climate Medicine Program

Household air pollution and COPD: cause and effect or confounding by other aspects of poverty?

K Mortimer
M Montes de Oca
S Salvi
K Balakrishnan
R M Hadfield
A Ramirez-Venegas
D M G Halpin
B Ozoh Obianuju
K Han MeiLan
R Perez Padilla
B Kirenga
J R Balmes
2022
SETTING

Household air pollution (HAP) and chronic obstructive pulmonary disease (COPD) are both major public health problems, reported to cause around 4 million and 3 million deaths every year, respectively. The great majority of these deaths, as well as the burden of disease during life is felt by people in low- and middle-income countries (LMICs).

OBJECTIVE AND DESIGN

The extent to which HAP causes COPD is controversial; we therefore undertook this review to offer a viewpoint on this from the Global Initiative for COPD (GOLD).

RESULTS

We find that while COPD...

The SARS-CoV-2 Pandemic: Real-Time Training and Service for Preventive Medicine Residents

Lisa A Miller
HRSA-Funded Preventive Medicine Residency Program Directors Workgroup*
2021

The 2020 SARS-CoV-2 pandemic created a unique opportunity for Public Health/General Preventive Medicine (PH/GPM) and Occupational and Environmental Medicine (OM) residents to contribute to pandemic public health response activities. We surveyed all 18 Health Resources and Services Administration (HRSA)-funded PH/GPM and OM residency program directors to evaluate program and resident involvement in pandemic response activities from January 1 through June 30, 2020. Of 116 residents, 110 (95%) participated at some level in the response activities including screening/testing, contact tracing,...

Testing for SARS-CoV-2 in Symptomatic Vaccinated and Unvaccinated Health Care Workers During the Delta Variant Surge

Anthony Lopez
Robert Kosnik
Paul D Blanc
Brian R Taylor
Sandeep Guntur
2021
Background:

Infection with SARS- CoV- 2 in health care workers (HCWs) challenges employee health services.

Methods:

We analyzed telephone Coronavirus Disease 2019 (COVID-19) hotline data over 8 weeks in 2021 during SARS- CoV- 2 Delta variant surge. We calculated COVID-19 case rates among persons-under-investigation (PUIs) for illness at two health care centers (HCs).

Results:

There were 41 COVID-19 cases among the 285 PUIs (14.4%) at the study HC and 549 (16.9%) of 3244 at the comparison HC. At the study HC, 11.7% of vaccinated PUIs versus 36.6% of unvaccinated...

Predicting Parkinson's Disease and Its Pathology via Simple Clinical Variables

Ibrahim Karabayir
Liam Butler
Samuel M Goldman
Rishikesan Kamaleswaran
Fatma Gunturkun
Robert L Davis
G Webster Ross
Helen Petrovitch
Kamal Masaki
Caroline M Tanner
Georgios Tsivgoulis
Andrei V Alexandrov
Lokesh K Chinthala
Oguz Akbilgic
2022

Background: Parkinson's disease (PD) is a chronic, disabling neurodegenerative disorder.

Objective: To predict a future diagnosis of PD using questionnaires and simple non-invasive clinical tests.

Methods: Participants in the prospective Kuakini Honolulu-Asia Aging Study (HAAS) were evaluated biannually between 1995-2017 by PD experts using standard diagnostic criteria. Autopsies were sought on all deaths. We input simple clinical and risk factor variables into an ensemble-tree based machine learning algorithm and derived...

Systematic Review of Ozone Effects on Human Lung Function, 2013 Through 2020

Stephanie M Holm
John R Balmes
2021
Background

Ozone effects on lung function are particularly important to understand in the context of the air pollution-health outcomes epidemiologic literature, given the complex relationships between ozone and other air pollutants with known lung function effects.

Research Question

What has been learned about the association between ozone exposures and lung function from epidemiology studies published from 2013 through 2020?

Study Design and Methods

On March 18, 2018, and September 8, 2020, PubMed was searched using the terms health AND ozone,...

No fire without smoke (particles)

Stephanie M Holm
John Balmes
2021

Pollution from landscape fires, which are increasing with climate change, leads to babies being born with lower birthweights in low- and middle-income countries.

Coccidioidomycosis and COVID-19 Co-Infection, United States, 2020

Alexandra K Heaney
Jennifer R Head
Kelly Broen
Karen Click
John Taylor
John R Balmes
Jon Zelner
Justin V Remais
2021

We review the interaction between coronavirus disease (COVID-19) and coccidioidomycosis, a respiratory infection caused by inhalation of Coccidioides fungal spores in dust. We examine risk for co-infection among construction and agricultural workers, incarcerated persons, Black and Latino populations, and persons living in high dust areas. We further identify common risk factors for co-infection, including older age, diabetes, immunosuppression, racial or ethnic minority status, and smoking. Because these diseases cause similar symptoms, the COVID-19 pandemic...

Letter from California, USA

Sheiphali A. Gandhi MD, MPH
2020

On the morning of 9 September 2020, residents of the San Francisco Bay Area awoke to an eerie orange light filtering through the windows (Fig. 1). Over the next day, post-apocalyptic images of the glowing, ash-filled sky flooded social media and became a global news focus. Air quality sharply decreased to unhealthy levels as ash particles fell to the ground. This alarming event was the result of a dry lightning storm that occurred 3 weeks before. During this storm, more than 12 000...

Effects of short-term increases in personal and ambient pollutant concentrations on pulmonary and cardiovascular function: A panel study analysis of the Multicenter Ozone Study in oldEr subjects (MOSES 2)

M W Frampton
J R Balmes
P A Bromberg
M Arjomandi
M J Hazucha
S W Thurston
N E Alexis
P Ganz
W Zareba
P Koutrakis
K Thevenet-Morrison
D Q Rich
2021

Background: The cardiovascular effects of ozone exposure are unclear. Using measurements from the 87 participants in the Multicenter Ozone Study of oldEr Subjects (MOSES), we examined whether personal and ambient pollutant exposures before the controlled exposure sessions would be associated with adverse changes in pulmonary and cardiovascular function.

Methods: We used mixed effects linear regression to evaluate associations between increased personal exposures and ambient pollutant concentrations in the 96 h before the pre-exposure visit, and 1)...